Detalhe da pesquisa
1.
A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies.
Nat Methods
; 19(12): 1599-1611, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36303018
2.
Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.
Nature
; 570(7759): 71-76, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31118516
3.
Re-analysis and meta-analysis of summary statistics from gene-environment interaction studies.
Bioinformatics
; 39(12)2023 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38039147
4.
High-throughput genetic clustering of type 2 diabetes loci reveals heterogeneous mechanistic pathways of metabolic disease.
Diabetologia
; 66(3): 495-507, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36538063
5.
Genome-wide gene-diet interaction analysis in the UK Biobank identifies novel effects on hemoglobin A1c.
Hum Mol Genet
; 30(18): 1773-1783, 2021 08 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33864366
6.
STAAR workflow: a cloud-based workflow for scalable and reproducible rare variant analysis.
Bioinformatics
; 38(11): 3116-3117, 2022 05 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35441669
7.
Impact of Rare and Common Genetic Variants on Diabetes Diagnosis by Hemoglobin A1c in Multi-Ancestry Cohorts: The Trans-Omics for Precision Medicine Program.
Am J Hum Genet
; 105(4): 706-718, 2019 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31564435
8.
Breast cancer polygenic risk scores are associated with short-term risk of poor prognosis breast cancer.
Breast Cancer Res Treat
; 196(2): 389-398, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-36138293
9.
GEM: scalable and flexible gene-environment interaction analysis in millions of samples.
Bioinformatics
; 37(20): 3514-3520, 2021 10 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-34695175
10.
Multi-ancestry genome-wide gene-sleep interactions identify novel loci for blood pressure.
Mol Psychiatry
; 26(11): 6293-6304, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33859359
11.
Efficient gene-environment interaction tests for large biobank-scale sequencing studies.
Genet Epidemiol
; 44(8): 908-923, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32864785
12.
A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure.
Hum Mol Genet
; 28(15): 2615-2633, 2019 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31127295
13.
A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.
Am J Hum Genet
; 102(3): 375-400, 2018 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29455858
14.
Clinical and metabolomic predictors of regression to normoglycemia in a population at intermediate cardiometabolic risk.
Cardiovasc Diabetol
; 20(1): 56, 2021 02 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33639941
15.
Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits.
Am J Hum Genet
; 100(6): 865-884, 2017 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28552196
16.
Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions.
Am J Epidemiol
; 188(6): 1033-1054, 2019 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30698716
17.
Testing the role of predicted gene knockouts in human anthropometric trait variation.
Hum Mol Genet
; 25(10): 2082-2092, 2016 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26908616
18.
An Empirical Comparison of Joint and Stratified Frameworks for Studying G × E Interactions: Systolic Blood Pressure and Smoking in the CHARGE Gene-Lifestyle Interactions Working Group.
Genet Epidemiol
; 40(5): 404-15, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27230302
19.
Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases.
PLoS Genet
; 8(5): e1002741, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22693455
20.
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.
PLoS Genet
; 8(3): e1002607, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22479202